In the past years, CBD products like CBD oil, CBD gummies, etc., has gained a huge amount of interest among consumers, scientists, and clinicians. Do you know why?
Evidence suggests that CBD prevents various adverse effects of THC, but many animal studies and evidence from human experimental and clinical studies suggest that CBD has powerful anti-anxiety properties. CBD can be safe, well tolerated, and beneficial to treat many anxiety-related disorders such as:
- Mild to moderate depression
- Panic disorder
- Social phobia
- Post-Traumatic Stress Disorder (PTSD)
- Obsessive Compulsive Disorder (OCD)
- Generalized Anxiety Disorder (GAD)
Beyond individual’s glowing testimonials about how CBD oil has successfully treated their anxiety, there are viable evidence-based on researches and tests performed on rodents that clearly suggests that CBD actually helps in relieving anxiety and stress.
Human experiments are legally complicated as well as costly, which is no surprise that human studies are lesser in number and also less conclusive. Overall, exciting uses of using CBD in anxiety have emerged for both humans and rodents:
Less anxiety in response to stress:
In these experiments, the test subjects are put in a stressful situation, and their anxiety level is measured.
The Rodent Evidence:
Few mice were placed in a cage with a boa constrictor. The mice that were given low doses of CBD spent more time observing and scanning their environment instead of panicking and running here and there in the cage.
The Human Evidence:
Public speaking is equivalent to the boa constrictor in humans. Giving CBD doses to a few people displayed improved performance both for people with social anxiety disorder and without an anxiety disorder.
How can CBD oil help heal anxiety and stress?
CBD oil generally works with CB1, which is a brain receptor and it creates a positive balancing impact on glutamate levels and GABA associated with reducing anxiety and stress. Receptors are miniature proteins attached to your cells that receive chemical signals from distinct stimuli and help your cells to respond.
How CBD affects CB1 is not completely understood. However, research shows that it alters the serotonin signals. Serotonin is a chemical in the human body that plays a major role when it comes to mental health. So, low serotonin levels are very common in depression and to not having enough serotonin can cause anxiety.
CBD oil is an anti-anxiety and anti-inflammatory compound. Studies show that CBD oil is one of the natural anxiolytics (anxiety calmer) and is efficacious in treating social anxiety. Most of the time CBD calms anxiety naturally without any potential side effects of any other anti-anxiety medications.
CBD oil directly affects the brain and lowers the activity in the amygdala and improves prefrontal cortex activation, the two most important part of the brain involved in anxiety.
Research and Evidence
Several studies find out the potential advantages of CBD oil for the treatment of anxiety. It has been observed by the National Institute on Drug Abuse that CBD has been applied to overcome stress in the animal. The risk of heart disease has dramatically reduced along with behavioral symptoms of anxiety.
In 2011, a study on human confirmed that 400 milligrams of oral CBD dose aides to reduce the anxiety levels. Further studies have revealed fascinating benefits of CBD oil for different sorts of stress like post-traumatic stress disorder and social anxiety disorder. CBD oil has been found useful in neurological disorder because of some antipsychotic benefit present in CBD. During a study in 2016 specialists suggested consumption of CBD over antipsychotic drugs to evade the chance of side effect.
On the other hand, after the extensive review of CBD in psychiatric disorder, some authors concluded that CBD oil is not the proper medication for depression. According to the report, more human tests are necessary to reach at a conclusion regarding the number of dosages and behavior of side effects. However, some positive results are remarked by many authors.
CBD Oil: How much should you take?
Most of the studies used different types of doses which vary from milligrams to hundreds of milligrams. The quantity slowly increases to check their result over a period of time. Even though CBD is usually very reliable, it is advisable to consume it as prescribed by the doctor. It should not be divided into dosage or consumed the whole daily portion in one time in order to experiment on the body.
CBD oil comes in a different range of concentrations such as in form of capsule or dropper bottles. The quantity of CBD can easily be found on the packaging of bottle and capsule. The quantity ranges from 250 mg to 1000 mg. In certain CBD oil define the concentration as percentages instead figure like 4% or 20% cannabidiol.
There are a large number of CBD oil available on the market. People prefer to choose products from the store like CBDinit where all the products are tested by the third party users for quality and strength.
CBD Oil: What are the side effects?
In the journal current drug safety, it has been published that in comparison to drugs, CBD has a minor side effect in several medical conditions. However, these considerations maintained data on the ratio of THC:CBD. The most common side effects of CBD treatment are changes in both weight and appetite, tiredness and diarrhea. Apart from these side effects of CBD produce mood changes and gastrointestinal discomfort. CBD does not have any adverse effect on blood pressure, heart rate and psychomotor functions.
Current preclinical and human findings often include dosing of CBD oil in healthy subjects. Although current conclusions are restrained by small sample volumes and a shortage of autonomous replication. The sign of neurobiological points the anxiolytic effect of CBD which includes altered medial prefrontal-amygdala connectivity and decreased amygdala activation. So, further studies are needed to confirm whether CBD dosing has similar consequences in relevant clinical states. In the medication of anxiety disorders, this article highlights the potential value and necessity for further research of CBD.