CBD has some unique neurological properties that are contributing to the oil’s growing popularity. Cannabidiol being nonpsychoactive is a feasible medication against mental problems like anxiety and depression; it is the easiest way to feel relaxed without undergoing intoxication. It doesn’t bind to the CB1 and CB2 receptors of the brain, which are concerned with emotional and sensory perception; memory and cognition. This is why CBD doesn’t induce a mind-altering state. Instead, it leads to a host of healing benefits due to its medicinal properties, the first one of which are its neuroprotective effects.
That means CBD protects neurons from degenerating with age. This particularly applies to Alzheimer’s; CBD hinders the progress of Alzheimer’s and cuts down upon the symptoms.
Next, it’s about the analgesic effects of CBD. It suppresses pains, including chronic and nerve pains. It inhibits neural transmissions of pain sensations without causing tolerance.
Then, CBD also has antitumor effects, including tumors of the brain, including malignant tumors. It is highly effective for treating Post-Traumatic Stress Disorders too.
CBD does that by acting through different receptor-independent channels, either by enhancing or by inhibiting particular protein-coupled receptors from their binding actions. The receptor systems it affects are:
• Serotonin System: The serotonin 1A receptor in the brain is targeted by CBD to deliver its therapeutic effects over release of hormones (e.g. cortisol and oxytocin) to regulate metabolism and the body’s response to stress. This directly affects a person’s social behaviour, mood, cognition and also, appetite. CBD enhances the way these receptors are activated and impedes neuropathic pain, anxiety, schizophrenia, depression – even nausea resulting from chemotherapy.
• Vanilloid system: This comprises TRPV1 receptors, which form an ion channel and controls thermoregulation, inflammation, and perception of pain.
• Orphan Receptors: That’s the GPR55 receptor and we still don’t know which receptor family tree it belongs to. It modulates blood pressure and bone re-absorption, which in turn determines bone density. It also controls cell division and metastasis of cancer. With CBD, GPR55 signaling can be blocked and proliferation and spreading of cancerous cells can be inhibited.
However, the greatest among all neurological positive effects CBD brings, its power to inhibit ANANDAMIDE from re-uptakes and breakdowns. This increases endocannabinoid levels in the synapse between neurons, offering neuroprotective effects against seizures, neuronal injuries, and neuro-degeneration.